RGR Pharma provides product clinical trial information published in the CMAJ


Scientific Literature


1. Bucalo, Mirikitani and Moy study entitled: Comparison Of Skin Anesthetic Effect Of Liposomal Lidocaine, Non Liposomal Lidocaine And EMLA Using 30 Minute Application Time.

2. Lener BS et al. Topical Anesthetic Agents in Dermatologic Surgery. Dermatolog Surg 1997; 23:673-683.

3. Friedman P et al. Comparative Study of the Efficacy of Four Topical Anesthetics. Dermatol Surg 25:12December 1999.

4. Finkel J.C., Yang C.I., Yarvitz J.L., Patel K.M., Neuroselective Sensory Electrodiagnostic Evaluation of 4% Liposomal Lidocaine.

5. Axelrod, Eugene; Double blind comparative effectiveness of Maxilene and EMLA in decreasing pain associated with adult venipuncture; Ferndale Laboratories.

6. Eichenfield L.F., Funk A., Cunningham B.B., et al., A Clinical study to evaluate the efficacy of Maxilene (4% Liposomal Lidocaine) as compared to EMLA cream (Eutectic Mixture of local anesthetics) for pain reduction of venipuncture in children; Division of Pediatric and Adolescent Dermatology, San Diego, and Dept of Pediatrics and Medicine, University of California, San Diego School of Medicine.

7. Koppel R.A., Coleman K.M., Coleman III W.P., The Efficacy of EMLA versus Maxilene for pain relief in medium-depth chemical peeling: A Clinical and histopathologic evaluation; Dermatol Surg 26:1:January 2000.

8. Luhmann J., Hurt S., Shootman, M. Kenned R., A Comparison of Buffered Lidocaine Versus Ela-Max Before Peripheral Intravenous Catheter Insertions in Children; PEDIATRIACS Vol. 113 No. 3 March 2004.

9. Liposomal lidocaine to improve procedureal success rates and reduce procedural pain among children: a randomized controlled trial. Anna Taddio, Herpreet Kaur Soin, Suzanne Schuh, Gideon Koren, and Dennis Scolnik CMAJ 2005 172: 1691-1695