AFAs Have Little Irritation Compared to AHAs
There is little irritation with the AFA Gels when compared to even neutralized AHAs. This may be due to the effect of the amino group that is retained in the AFA molecule, which might modify the causticity of the AFAs without changing the overall pH of the molecule. The addition of purines to the AFA Gels also serves to attenuate any potential irritation or causticity.